Check with your doctor immediately if any of the following side effects occur: More common. Bladder pain bloating or swelling of the face, arms, hands, lower legs, or feet bloody or cloudy urine decreased urine difficult, burning, or painful urination dry mouth fever frequent urge to urinate increased thirst irregular heartbea The balance of treating the patient's serious infection while making sure they do not receive too much medication is delicate, as side effects of too much vancomycin can be dangerous. Vancomycin side effects include the following 3: Kidney damage (nephrotoxicity) Hearing loss (ototoxicity) Red man or red person syndrome; Other less common side effects such as: allergic reactions: hives, difficulty breathing or wheezing; Low white blood cells (neutropenia) or high eosinophil.
cough or hoarseness. dizziness or lightheadedness. feeling of constant movement of self or surroundings. feeling of fullness in the ears. fever with or without chills. general feeling of tiredness or weakness. hearing loss. loss of balance. lower back or side pain Side effects of Vancomycin include: serious allergic reactions (anaphylactoid reactions), including low blood pressure, wheezing, indigestion, hives, or. itching. Rapid infusion of Vancomycin may also cause flushing of the upper body (called red neck or red man syndrome), dizziness . Common vancomycin side effects may include: low potassium; nausea; or. stomach pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 Common side effects of vancomycin injection include pain, redness, and tenderness at the injection site. Serious side effects of vancomycin injection include ringing in the ears, hearing problems, change in the amount of urine, easy bleeding/bruising, fever, persistent sore throat, persistent diarrhea
Side effects of Vancomycin include: serious allergic reactions (anaphylactoid reactions), including low blood pressure, wheezing, indigestion, hives, or. itching. Rapid infusion of Vancomycin may also cause flushing of the upper body (called 'red neck' or 'red man syndrome'), dizziness Some of the most common side effects associated with vancomycin use include the development of an unusual taste in the mouth, stomach problems such as nausea and vomiting, allergic reactions, and even hearing or kidney damage. Individuals who develop the more serious side effects are typically encouraged to seek medical help as soon as possible
Side effects. Serum vancomycin levels may be monitored in an effort to reduce side effects, although the value of such monitoring has been questioned. Peak and trough levels are usually monitored, and for research purposes, the area under the concentration curve is also sometimes used. Toxicity is best monitored by looking at trough values Vancomycin is a prescription drug used to treat a certain intestinal condition (colitis) that may rarely happen after treatment with antibiotics. This condition causes diarrhea and stomach / abdominal pain. When vancomycin is taken by mouth, it stays in the intestines to stop the growth of bacteria that cause these symptoms Bleeding and Brusing Vancomycin IV can also cause abnormal bleeding or bruising 1. It can also cause severe blistering on the skin, especially on the upper body including the arms and hands, as well as on the legs and feet. These side effects are rare, but life-threatening
One of the Vancomycin side effects also includes blurring of vision which is transitory but the damage is permanent. Hence, there is a need to educate the person of this kind of side effect associated with the usage of Vancomycin. 5. CHILLS WHICH HAPPENS IN A PERIOD OF TIM Another long-term and potentially irreversible side effect of vancomycin is kidney damage 2. Vancomycin can be toxic and, therefore, may lead to kidney damage, abnormal kidney function and irreversible kidney failure 2 Side Effects. Pain, redness, and tenderness at the injection site may occur. If this medication is injected too fast, a condition known as red man syndrome may occur. Tell your doctor promptly. A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome A Type Of Blood Disorder With A Decrease In All Types Of Blood Cells Called Pancytopenia A Type Of Kidney..
Common side effects of vancomycin include lightheadedness or faintness, upset stomach, itching, difficulty breathing, or a rash on the face, neck, chest, or upper arms or legs. Vancomycin can also cause dizziness. Do not drive or operate heavy machinery until you know how vancomycin affects you Vancomycin is used to treat an infection of the intestines caused by Clostridium difficile, which can cause watery or bloody diarrhea. Vancomycin is also used to treat staph infections that can.. Side effects that can be experienced while taking this medication anaphylactic reaction, wheezing, indigestion, low blood pressure, and pain and spasm of the muscles of the back and chest [1, 2, 3,]. The Red Man Syndrome. There are reported instances wherein intravenous vancomycin is administered too rapidly . Less common side effects include back pain, muscle pain, and nausea, while side effects that are less common but more serious include bloody or watery diarrhea, ringing in the ears, and skin rash. A person who experiences any persistent or serious side effect should talk to his or. A possible side effect that may occur if vancomycin is infused too rapidly includes an allergic reaction (anaphylactoid reaction) known as red man syndrome. This is the most common allergic reaction in younger patients (under age 40) who received intravenous vancomycin. Red man syndrome consists of an itchy, hot, red rash that affects the upper body, face, and neck
Vancomycin (Vancocin) is an antibiotic used to treat cases of Clostridium difficile (C. Diff) and staphylococcal enterocolitis, both of which are intestinal infections that cause diarrhea. Review side effects, drug interactions, dosage, and pregnancy safety information prior to taking this medication. Multimedia: Slideshows, Images & Quizze Vancomycin can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, or pain or arthritis (including aspirin, Tylenol, Advil, and Aleve). Other drugs may affect vancomycin, including prescription and over-the-counter medicines, vitamins, and herbal. Side-effects, further information. Vancomycin is associated with a higher incidence of nephrotoxicity than teicoplanin. Allergy and cross-sensitivity. Cross sensitivity. Caution if teicoplanin sensitivity. All patients require serum-vancomycin measurement (on the second day of treatment, immediately before the next dose if renal function.
Common Vancomycin Side Effects. Common side effects of vancomycin will vary depending on how the medication is taken. Injectable forms of vancomycin are thought to cause pain and irritation at the injection site as well as ringing in the ears. Oral versions of vancomycin are thought to produce mouth irritation, nausea, and a bitter taste in the mouth occur. Other related-side effects include ototoxicity, neutropenia, fixed drug eruptions, fever, phlebitis, nephrotoxicity [1-3], thrombocytopenia  and rarely, pancytopenia and Stevens-Johnson syndrome [5,6]. We report two cases of uncommon vancomycin-related side effects and review literature through Medline from 1956 to 2000 (Key-words: vancomycin As a rule, the most frequent side effects of vancomycin are fatigue or nausea. The main intervention that can help patients who suffer these more common side effects is to rest and inform a doctor about any reaction. Pain that does not disappear in one hour makes it imperative to contact a doctor Side effects that can be experienced while taking this medication anaphylactic reaction, wheezing, indigestion, low blood pressure, and pain and spasm of the muscles of the back and chest [1, 2, 3,]. The Red Man Syndrome There are reported instances wherein intravenous vancomycin is administered too rapidly Although vancomycin is safe in therapeutic serum concentrations, it may cause many side effects such as neutropenia, fever, phlebitis, nephrotoxicity, ototoxicity, thrombocytopenia . Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome has also been described as a violent reaction accompanied by drug
Bladder pain, decreased urination, blood in the urine, and even problems with heart rate can occur as side effects of this drug. If these side effects occur, a patient should see the doctor right.. . Ein on side effect of vancomycin: AT AGE 47, SOMETIMES THE CYCLES ARE IRREGULAR, SOMETIMES HEAVIER, WHETHER YOU ARE ON HEPARIN OR NOT ON HEPARIN
. In a controlled clinical study, potential ototoxic and nephrotoxic effects of vancomycin on infants were evaluated when administered to pregnant women for serious staphylococcal infections complicating IV drug abuse. Single-dose flexible bags onl The effects of combining vancomycin with other drugs have been studied by many investigators. Effective combinations of vancomycin with β-lactams including carbapenem drugs have previously been reported. 2,3,4 However, these results were generally obtained in vitro, and corresponding in-vivo effectiveness has not always been confirmed. side effects. A 2015 review article described the most com-mon adverse effects of vancomycin. Red-man syndrome, hypersensitivity reactions, reversible neutropenia, thrombo-cytopenia and agranulocytosis, ototoxicty, and nephrotox-icity all continue to be reported in the literature. Red-man syndrome is cited as the most common side effect, an Vancomycin is used for Bacterial Septicemia, Endocarditis, Osteomyelitis etc. Know Vancomycin uses, side-effects, composition, substitutes, drug interactions. Introduction. Vancomycin is a time-dependent antibiotic with bactericidal activity useful for treating patients with infections caused by Gram-positive microorganisms, including methicillin-resistant Staphylococcus aureus. It presents a 2 or 3 compartment pharmacokinetic profile and high interindividual variability, which result in the need for a routine therapeutic drug monitoring (TDM)
Certain side effects may occur if your body absorbs vancomycin through the intestinal walls. Call your doctor at once if you have: increased diarrhea that is watery or bloody; hearing loss, ringing in your ears; kidney problems-swelling, rapid weight gain, pain in your side or lower back, little or no urinating; o Despite its effectiveness against CDI (cure rate of ∼90%), a subset of cured patients (14%-21%) develop recurrent infections, which are thought to be enhanced by microbiota changes promoted by vancomycin. 8, 9 In addition, microbiota alterations induced by vancomycin may promote intestinal colonization by other pathogens, including VRE, Klebsiella pneumoniae or Escherichia coli. 10 Moreover, oral vancomycin therapy may predispose to other microbiota-related disorders, including obesity. Vancomycin is a bactericidal glycopeptide antibiotic with activity against most Gram positive bacteria. It is particularly effective against methicillin-resistant Staphylococcus aureus and other multi-drug resistant organisms. Vancomycin has a plasma half-life of 4 to 6 hours. Glomerular filtration eliminates 90% of an intravenous dose over 24.
If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Vancomycin medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively Vancocin (vancomycin) is effective in treating C. difficile-associated diarrhea or Staph infection of the small intestine and colon. Vancocin (vancomycin) is only given by mouth to treat C. difficile-associated diarrhea or Staph infection of the small intestine and colon. It is not effective for other types of infections Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. breathing difficulty. change in amount, color of urine. change in hearing. dizziness. fever, infection How much did GOP rep exaggerate Paralympic claim? Biden signs executive order improving stimulus aid. 'Big Bang' star clarifies stance on coronavirus vaccination Usage of Vancomycin without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant
Description: Vancomycin is a glycopeptide antibiotic which binds tightly to D-alanyl-D-alanine portion of cell wall precursor, blocking glycopeptide polymerisation leading to the inhibition of bacterial cell wall synthesis.It also impairs bacterial-cell-membrane permeability and RNA synthesis. Pharmacokinetics: Absorption: Poorly absorbed from the gastrointestinal tract Information about VANCOMYCIN (VANCOCIN): Side effects, uses, dosage, warnings, precautions, indications, mechanism of action (moa), brand name (Vancocin) a.. Vancomycin is an anti-infective agent covering gm+v infections including MRSA. It is known as the gold standard for treating MRSA infections. Vancomycin is popular for its nephrotoxicity and ototoxicity along with Red Man Syndrome. How to remember the side effects of Vancomycin? NOT RED. Although it is RED! anyway lets break it: N : N.
Vancomycin is largely well tolerated; common side effects include diarrhea, nausea, nephrotoxicity and neutropenia. Vancomycin mechanism of action Vancomycin is a glycopeptide antibiotic that exerts its bactericidal effect by inhibiting the polymerization of peptidoglycans in the bacterial cell wall Vancomycin can be used to treat colitis, a bacterial infection of the intestines. As with any medication, there is a possibility, when taking vancomycin, of developing serious side effects or an allergic reaction. While these conditions require prompt medical treatment, vancomycin toxicity is a different type of problem Infusion-related events, nausea, drug fever, rash (may be serious, eg, Stevens-Johnson syndrome), ototoxicity, nephrotoxicity, thrombophlebitis, blood dyscrasias; rare: interstitial nephritis,.. Vancomycin is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive bacteria. Questions and answers on Vancomycin Suggest dosage for Vancomycin
Vancomycin was first approved for use in the United States in 1958 and it continues to be widely used, particularly with the recent rise in incidence of serious MRSA infections. Vancomycin is largely well tolerated; common side effects include diarrhea, nausea, nephrotoxicity and neutropenia Vancomycin is a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall. Val-Vancomycin: Vancomycin belongs to the group of medications known as antibiotics. It works by killing the bacteria that are causing the infection. The oral form is used to treat certain infections of the gastrointestinal tract. The intravenous (IV) form of this medication is used to treat serious or life-threatening infections that have not been successfully treated with other antibiotics.
SIDE EFFECT OF VANCOMYCIN . Vancomycin Vancocin Bad Drug , Lecture 6: Antimicrobials , Antibiotics; How Do They Work? Clinical Education , How to Treat a Staph Infection: Symptoms, Treatment , Evolutionary war between microorganisms affecting human , Antibiotics , Endophthalmitis , Module 12: Infectious Diseases Part 1 Nurse Practitioner , Antibiotics nursingì— ê´€í•œ ìƒ ìœ. Rapid infusion of vancomycin causes histamine-mediated side effects, hypotension, and rash, known as red man syndrome
Even though vancomycin is known to be a relatively safe drug, it may have side effects like fever, red man syndrome, phlebitis, nephrotoxicity, autotoxicity, thrombocytopenia, fixed drug eruption. Vancomycin Is Known To Interact With Other Drugs Like Amphotericin B, Cyclosporin A, Gentamicin, Metformin (HCl), Netilmicin (Sulphate), Oxaliplatin, Streptomycin, Tobramycin. Always Consult Your Physician For The Change Of Dose Regimen Or An Alternative Drug Of Choice That May Strictly Be Required. Side effects of Vancomycin Side effects of Vancomycin, are black muddy stools? By proceeding further you accept the Terms and Condition Two hours after VCM was inhaled, serum VCM concentrations were unmeasurable in 7 patients. The VCM level in sputum peaked at 262.5 micrograms/g just after inhalation, and then gradually decreased. No side effects of this treatment were observed. These results suggest that inhaled VCM can be used to eliminate MRSA Vancomycin is used to treat an infection of the intestines caused by Clostridium difficile, which can cause watery or bloody diarrhea. Vancomycin is also used to treat staph infections that can cause inflammation of the colon and small intestines. Oral vancomycin works only in the intestines
Vancomycin-Induced Neutropenia M. Narita, M.D. Epidemiology Neutropenia is considered a rare side effect of vancomycin therapy. The incidence of vancomycin-induced neutropenia has been estimated to be 2-8% based on retrospective analyses in hospitalized patients (1, 2). The incidence of infection INTRODUCTION. Vancomycin is a glycopeptide antibiotic administered intravenously for treatment of patients with suspected or proven invasive gram-positive infections, including methicillin-resistant Staphylococcus aureus.. Appropriate dosing and administration of vancomycin requires consideration of the pathogen, type and severity of infection, patient weight, and kidney function  Intestinal inflammation: People with conditions associated with inflammation of the intestines (e.g., Crohn's disease, ulcerative colitis) may be at higher risk for side effects, when they take vancomycin capsules, especially if they also have impaired kidney function. Your doctor will monitor you closely for side effects Most importantly, though, there is a greater understanding of antibiotic side effects. Being aware of the side effects that antibiotics can cause will hopefully lead to even fewer unnecessary antibiotic prescriptions for colds and other viral infections so that antibiotics will work when we need them See also Antimicrobial guidelines. Key Points. Administer vancomycin intravenously (IV) over at least 1 hour. Rapid infusion may cause red man syndrome (see Adverse Effects).Vancomycin levels are required to ensure that the target therapeutic range is achieved (see Therapeutic Drug Monitoring).; Continuous infusions of vancomycin in infants aged 0 to 90 days are associated with earlier and.
Although vancomycin is a commonly prescribed antibiotic, linear IgA bullous dermatosis is an under-recognized potential side effect. The onset of vesicles and bullae after the administration of this antibiotic should raise suspicion of this blistering skin disease Side Effects for VANCOMYCIN HYDROCHLORIDE (capsule) are also known as adverse reactions. Below is a summary of known side effects for vancomycin hydrochloride
Read the side effects of Vancomycin as described in the medical literature. In case of any doubt consult your doctor or pharmacist. Most Common - Ear and kidney damage In a prospective study to determine if standardized vancomycin doses could produce adequate serum concentrations in 25 full-term neonates with sepsis, 13 ha . Vancomycin is associated with the following range of side effects: Thrombophlebitis - if administered by infusion. For this reason, vancomycin should not be administered too rapidly otherwise serious infusion reactions can take place. Red man syndrome - is the name given to one of these anaphylactoid reactions. As the name suggests, it causes upper body erythema - as well as pruritis This is not a complete list of possible side effects. If you notice other effects not mentioned above, contact your doctor or pharmacist. Precautions with Vancomycin. Before taking vancomycin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies
Vancomycin is an antibiotic that is used to treat severe infections that are resistant to certain other antibiotics. Vancomycin is also used to treat serious infections in people who are allergic to penicillin. Vancomycin may also be used for purposes not listed in this medication guide These are the most common side effects, but there may be others. Please report all side effects to the doctor or nurse. In case of a severe side effect or reaction, call the doctor, nurse, or pharmacist at 901-595-3300. If you are outside the Memphis area, dial toll-free 1-866-2STJUDE (1-866-278-5833). Special instructions for vancomycin Vancomycin enters breast milk, and so its use during breastfeeding is discouraged to prevent disruption of gastrointestinal microflora; however, because oral absorption is poor from a normal gastrointestinal tract, systemic adverse effects in infants are unlikely side effects of vancomycin . By berkie176163265 | 1 post, last post over a year ago. New Reply Follow New Topic. berkie176163265 over a year ago. I have a serious bacterial infection in my mouth, and my dentist prescribed me an antibiotic I have never heard about before. It is called vancomycin and I am about to tae my first dosage Vancomycin is considered as a generally safe medication, but it is well known that vancomycin can cause histamine-mediated side effects, hypotension, and rash, well known as red man syndrome
J01XA01 - vancomycin ; Belongs to the class of glycopeptide antibacterials. Used in the systemic treatment of infections. Disclaimer: This information is independently developed by CIMS based on vancomycin from various references and is provided for your reference only RESULTS: The main adverse effects of vancomycin are: hypotension, phlebitis, nephrotoxicity, ototoxicity, hypersensitivity reactions, red man syndrome, neutropenia, chills, fever, interstitial nephritis Side Effects for VANCOMYCIN HYDROCHLORIDE (injection, powder, lyophilized, for solution) are also known as adverse reactions. Below is a summary of known side effects for Vancomycin Hydrochloride Vancomycin capsules are generally not absorbed into your bloodstream and are therefore unlikely to cause any side-effects. You may be more at risk of the medicine getting into your bloodstream (and hence more at risk of side-effects) if you have an inflammatory bowel condition Toxicity. The oral LD 50 in mice is 5000 mg/kg. The median lethal intravenous dose is 319 mg/kg in rats and 400 mg/kg in mice. Label. Conversely, the most common adverse effects associated with vancomycin appear to be nausea, abdominal pain, and hypokalemia Label.In particular, incidences of hypokalemia, urinary tracy infection, peripheral edema, insomnia, constipation, anemia, depression.
Side Effects of Vancomycin - Free download as Word Doc (.doc / .docx), PDF File (.pdf), Text File (.txt) or read online for free Vancomycin is the only treatment in the case of sepsis and infection in the lower respiratory tract occurring because of the same bacteria. Side effects of this drug: Here are the common side effects of this antibiotic: 1.Pain in the injected area along with allergic reactions and thrombophlebitis. 2. Hearing loss. 3. Hypotension. 4. Bone marrow suppressio Common side effects include pain in the area of injection and allergic reactions. Occasionally, hearing loss, low blood pressure, or bone marrow suppression occur. Safety in pregnancy is not clear, but no evidence of harm has been found, and it is likely safe for use when breastfeeding. It is a type of glycopeptide antibiotic and works by blocking the construction of a cell wall. Vancomycin was first sold in 1954. It is on the World Health Organization's List of Essential Medicines. The World H Vancomycin can cause serious side effects. If you lose your hearing, have a ringing in your ears, are urinating less, feel lightheaded or faint or if you have fever, chills, aches, flu-like symptoms, a rash, skin redness, bruising, tingling, numbness, pain, weakness, stomach pain or bloody or watery diarrhea, do not take any more vancomycin and talk to your doctor immediately
Summary Statistics Reports of VANCOMYCIN causing SUPERINFECTION: 10 Reports of any side effect of VANCOMYCIN : 15265 Percentage of VANCOMYCIN patients where SUPERINFECTION is a reported side effect: 0.0655% FDA reports of any drug causing SUPERINFECTION : 689 Average percentage for all medicated patients where SUPERINFECTION is reported as a complication: 0.0043 Vancomycin shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice. Severe . Is the use of Vancomycin Injection safe during breastfeeding? Breastfeeding women can safely use Vancomycin . Safe To prevent infections local delivery of antibiotics is a useful tool. Especially in bone fractures, vancomycin impregnated bone cements are often used allowing high concentrations of antibiotics at the infection side without high serum concentrations. However, besides potential pathogens, cells involved in tissue regeneration may also be affected by the drug. We investigated the effect of.
Common side effects of vancomycin hydrochloride may include nausea, dizziness, back pain, and muscle pain. Other, more serious side effects may include hearing loss, inability to urinate, fever, chills, flu-like symptoms, lightheadedness or fainting, rash or bruising, numbness, weakness, tingling, stomach pain, and bloody diarrhea Vancomycin injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: pain, redness, or swelling at the injection site; fever; nausea; chills; Some side effects can be serious Safety of vancomycin with or without gentamicin in neonates. Linder N, Edwards R, MeClead R, Mortensen ME, Walson P, Koren G. Short- and long-term side effects of vancomycin, or the combination of vancomycin and gentamicin, were retrospectively evaluated for 65 treatment courses in 47 premature infants who were exposed to high vancomycin serum.
About this FactMed analysis covering adverse side effect reports of VANCOMYCIN patients who developed MACULAR FIBROSIS. FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products Side Effects. There may be pain in the abdomen, nausea, or vomiting. If any of these effects gets worse or worse, then tell your doctor or pharmacist immediately. Remember that your doctor has prescribed Vancomycin because he or she has decided that the benefit is higher than the risk of side effects. Many people using this drug do not have. Vancomycin is the first-line agent for the treatment of bacteremia, endocarditis, pneumonia, cellulitis, and osteomyelitis. Pancytopenia is an uncommon adverse effect of vancomycin therapy, with.
Vancomycin Side Effects Pain, redness, and tenderness at the injection site may occur. If this medication is injected too fast, a condition known as red man syndrome may occur. Tell your doctor promptly if you have symptoms such as flushing of the upper body, dizziness, or muscle pain/spasms of the chest and back. If any of these effects last. Vancomycin also inhibits transglycosylase (glycosyltransferase), a second enzyme responsible for cross-linking sugar residues, although this appears to be a less important mechanism compared to inhibition of transpeptidase. The mechanism for transglycosylase inhibition is unclear. Side Effects: Phlebosclerotic (vancomycin is irritating to. You may report side effects to Health Canada at 1-866-234-2345. Precautions Before taking vancomycin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies Vancomycin is an antibiotic. Oral (taken by mouth) vancomycin fights bacteria in the intestines. Vancomycin is used to treat an infection of the intestines caused by Clostridium difficile, which can cause watery or bloody diarrhea. Vancomycin is also used to treat staph infections that can cause inflammation of the colon and small intestines included studies revealed the rate of wound infection, side effects, and the results of the culture from the infected wound. Of the 20 studies, 18 showed that the use of intra-wound vancomycin powder might prevent SSI after spinal surgeries. However, 3 studies showed little evidence that it prevented SSI. The level of evidence (LOE) of the include